Abstract

BackgroundWhile some dietary patterns are associated with the incidence of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), the relationship between dietary pattern and risk factors for CVD in patients with T2DM remains to be clarified. The aim of this study was to identify dietary patterns and investigate the relationship between dietary patterns and potential risk factors for CVD in patients with T2DM.MethodsThe study participants comprised 726 Japanese T2DM outpatients free of history of CVD. Life styles were analyzed using self-reported questionnaires. The relationship between dietary patterns, identified by factor analysis, and potential risk factors for CVD was investigated by linear and logistic regression analyses.ResultsSix dietary patterns were identified by factor analysis. Especially, three dietary patterns were associated with risk factors for CVD. The “Seaweeds, Vegetables, Soy products and Mushrooms” pattern, characterized by high consumption of seaweeds, soy products and mushrooms, was associated with lower use of diabetes medication and healthier lifestyles. The “Noodle and Soup” pattern, characterized by high consumption of noodle and soup was associated with higher body mass index, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase and triglyceride levels. The “Fruit, Dairy products and Sweets” pattern was associated with lower γ-glutamyl transpeptidase levels, blood pressure, albuminuria and brachial-ankle pulse wave velocity.ConclusionsThe findings suggested that dietary patterns correlated with risk factors for CVD in T2DM patients.

Highlights

  • While some dietary patterns are associated with the incidence of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), the relationship between dietary pattern and risk factors for CVD in patients with T2DM remains to be clarified

  • We developed three models to evaluate the trend adjusted for age and gender or adjusted for age, gender, and body mass index (BMI), Morning Evening Questionnaire (MEQ), Pittsburg Sleep Quality Index (PSQI), beck depression inventory (BDI)-II, current smoking and physical activity

  • Among the six dietary patterns classified in this study, the “Seaweeds, Vegetables, Soy products and Mushrooms” pattern was associated with lower use of diabetes medications and healthier lifestyles

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Summary

Introduction

While some dietary patterns are associated with the incidence of type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), the relationship between dietary pattern and risk factors for CVD in patients with T2DM remains to be clarified. The aim of this study was to identify dietary patterns and investigate the relationship between dietary patterns and potential risk factors for CVD in patients with T2DM. In real life, people do not consume certain foods or single nutrients, but rather mixed food that contains various nutrients In this regard, the Osonoi et al Nutrition Journal (2016) 15:15 dietary pattern should be taken into consideration, because it reflects the complexity of dietary intake, where the food contents usually have interactive and synergistic effects and occasionally even antagonistic effects [11]. It was suggested that dietary patterns may be more predictive of disease risks compared to specific foodand nutrient-based approaches [11]

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