Abstract
Abstract Background: Demodex folliculorum is one of the most common types of microscopic ectoparasites that infect humans, It lives permanently in the hair follicles and causes Demodectic blepharitis and rosacea. Objectives: Evaluating the body’s immune response against infection with the Demodex follicular parasite, determining IgE levels, and evaluating the effect of some factors, such as gender and age, on infection with the Demodex follicular parasite. Materials and Methods: A total of 722 study samples were collected and examined comprising both males and females aged from 10 to 70 years. Results: results showed that infection with the parasite Demodex folliculorum had a highly significant effect (P ≤ 0.0 1) on the concentration of immunoglobulin E (IgE). A higher concentration of IgE was observed in the group of people with the parasite compared with the control group and for all age groups, and the increase was more pronounced. In the age group of 10–19 and 30–39 years, the IGE level was 81.03 and 88.69 IU/ml in the control group, and it increased significantly (P ≥ 0.01) to 466.20 and 456.34 IU/ml, respectively, in the infected group with the parasite. Conclusions: We conclude through the results of the current study that infection with the D. folliculorum parasite has a highly significant effect on the concentration of IgE immunoglobulin.
Published Version
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