Relationship between Cognitive Impairment and Serum ALP after Light Acute Ischemic Stroke in the Elderly

Abstract

Objective: To analyze the association between cognitive impairment and serum ALP levels in elderly patients who developed light acute ischemic stroke. Methods: 100 cases of elderly patients with mild acute ischemic stroke admitted from January 2022 to June 2023 were selected as the study subjects, and were divided into two groups according to whether or not they developed cognitive impairment within six months; those who did not develop cognitive impairment were classified into the control group, with a total of 62 cases, while those who developed cognitive impairment were classified into the case group, with a total of 38 cases. The general data and serum ALP levels of the two groups were compared, and the correlation between serum ALP levels and MoCA scores was analyzed. Results: There was no significant difference between the general information of the two groups of patients in the control group and the case group (P > 0.05). The serum ALP level of the patients in the case group was higher than that of the control group (P < 0.05), and there was a negative correlation between the serum ALP level and the total score of MoCA, the visuospatial and executive scores, and the memory score (P < 0.05). Conclusion: The serum ALP levels of elderly patients with cognitive impairment after mild acute ischemic stroke were higher than those of elderly patients without cognitive impairment after mild acute ischemic stroke, so the risk of cognitive impairment can be predicted in advance by detecting serum ALP levels.