Abstract

IN TWO EARLIER PAPERS (1, 2) the effect of various environmental conditions upon the growth of rats and upon the tensility of the aorta has been reported. These studies showed that the tensility factor (measured by the distention of an aortal ring under gradually increasing stress) varied with age, the aortae of older animals becoming progressively less resistant to a given tension. Under certain experimental conditions, the normal curve of tensility was profoundly modified. Rats kept at a low temperature (65°F.) had aortae with high tensility values, resembling those of much younger animals. Rats kept at a high temperature (95°F.), rats receiving thyroidextract, and rats exposed to long term nervous disturbance (intermittent bell ringing, air blasts,and cage vibration once each hour) all had aortae with low tensility resembling that of older animals.

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