Abstract

LUNING1 has shown that the rate of dominant lethals and gross rearrangements varies with the time from irradiation to insemination, with a peak around 7–10 days after the treatment. He suggests that the peak corresponds to irradiated spermatids which hence are supposed to be more sensitive than mature sperm. Auerbach2 claims that the sensitive stage, although it may include late meiosis, consists mainly of spermatid stages. Khishin3, comparing the mutation pattern from irradiation of larvae, pre-pupae and pupae, agrees with Auerbach. Fritz-Niggli4 adopted the same technique and deduced by analogy the following pattern of time-lapse between irradiated stages and insemination : mature sperm the 1st–4th day ; spermatids the 4th–7th day; meiosis the 7th–10th day ; and from the 10th day after irradiation spermatogonia.

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