Abstract
The aim of this study was to evaluate the risk factor of gallstone occurrence after distal gastrectomy (DG) for gastric cancer. Relevant documents published from 2000 to 2016 were retrieved in PubMed, Web of Knowledge, and Ovid's database, and a metaanalysis was performed with RevMan 5.0 software for odds ratios (ORs) and 95% confidence intervals (CIs). Eight studies met the final inclusion criteria. From the pooled analyses, nonphysiological reconstruction (OR = 1.51; 95% CI = 1.10-2.08; P = 0.01) and vagus nerve resection (OR = 2.79; 95% CI = 1.57-4.96; P = 0.0005) were significantly associated with increased risk of gallstone after DG. Our analysis indicated that digestive tract reconstruction and vagus nerve resection were strongly and consistently associated with gallstone formation after DG.
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