Effect of gastrojejunostomy Roux-en-Y anastomosis on gastrointestinal function and body mass index in patients with distal gastrectomy and gastrointestinal reconstruction

Abstract

Objective To investigate the effect of gastrojejunostomy Roux-en-Y anastomosis on gastrointestinal function and body mass index in patients with distal gastrectomy and gastrointestinal reconstruction. Methods From March 2013 to June 2016, 62 patients with distal gastrectomy were randomly divided into the control group (n=31) and the study group (n=31) according to the random number table method. The control group was treated with Billroth-I anastomosis, and the study group was treated with Roux-en-Y. The recovery of gastrointestinal function, complication rate, BMI and gastrointestinal hormone in serum [somatostatin (SS), cholecystokinin (CCK), motilin (MTL) and gastrin (GAS) level change] before and after surgery in the two groups were made statistical comparison. Results ①The function of gastrointestinal tract: the bowel sound time, eating time, anal exhaust time and defecation time in the study group were less than that in the control group, and the difference was statistically significant (P 0.05). The BMI of the study group was higher than that of the control group at 1 month and 3 months after operation (P 0.05). The level of SS and GAS in the study group were higher than that in the control group at 1 month after operation, and the level of CCK was lower than that in the control group (P 0.05). The incidence of inflammation of gastric relict [12.90% (4/31)] and reflux esophagitis [6.45% (2/31)] in study group, which were lower than those in control group [38.71% (12/31), 29.03% (9/31)], and the differences were statistically significant (P<0.05). Conclusions Gastric-jejunum Roux-en-Y anastomosis is helpful for early recovery of gastrointestinal function and body mass index in patients with distal subtotal gastrectomy, less effect on gastrointestinal hormones, lower incidence of reflux esophagitis and residual gastritis, and worthy of clinical popularization. Key words: Gastrojejunum Roux-en-Y anastomosis; Gastric cancer; Digestive tract reconstruction; Gastrointestinal function; Body mass index