Abstract

West Nile Virus (WNV) is the most common mosquito borne cause of viral encephalitis in the United States. Physical and neuro-cognitive recovery from WNND may be prolonged or incomplete leading to chronic cognitive inefficiencies and functional decline. There continues to be no effective treatment of WNV and current management is primarily supportive. The objective of this review is to evaluate the functional outcomes and role of rehabilitation services in subjects with WNND. The charts of five subjects admitted to an acute inpatient brain injury rehabilitation facility from June to December 2012 were retrospectively reviewed. (Mean, Range)-Age (64.8, 43–78 years), Admission Functional Independence Measure (FIM) (45.2, 14–63), Discharge FIM (82.2, 61–100), FIM score gain (37, 24–60), Cognitive FIM gain (7, 1–18), Mobility FIM gain (17.4, 13–20), ADL FIM gain (12.6, 4–23); acute brain injury inpatient rehabilitation facility length of stay (LOS) (17.8, 14–21 days); acute hospital LOS (15, 10–22 days). Of the five subjects, three were discharged home, one was discharged to a skilled nursing facility, and one was discharged to an assisted living facility. Subjects with WNND have significant functional decline across all FIM subcategories and may benefit from a course of brain injury-specific acute inpatient rehabilitation.

Highlights

  • From 1999 to 2019, the Centers for Disease Control and Prevention (CDC) reported over 51,000 cases of West Nile Virus (WNV) throughout the United States [1]

  • Subjects diagnosed with West Nile Neuro-invasive Disease who were admitted to a single acute inpatient brain injury rehabilitation facility between June and December 2012 were included in this review

  • No subjects admitted during this time frame with West NileNeuro-invasive Disease (WNND) were excluded from the study

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Summary

Introduction

From 1999 to 2019, the Centers for Disease Control and Prevention (CDC) reported over 51,000 cases of West Nile Virus (WNV) throughout the United States [1]. Factors that determine who is at risk for neuro-invasive disease remain unclear; individuals with advanced age are known to have greater severity of WNND [3,6,7]. Despite many of these individuals living independently prior to contracting the viral infection, physical and neuro-cognitive recovery from WNND may be prolonged or incomplete leading to chronic cognitive inefficiencies and functional decline in mobility and activities of daily living (ADLs)

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