Abstract

Adenoid cystic carcinoma is a cancer of the salivary gland that primarily affects the parotid, submandibular, and accessory salivary glands. Its growth is slow and it has infiltrative nature. A 46-year-old female patient coming from the rural area presented a lesion on the palate and reported pain in the region for three years. After incisional biopsy, and histopathological diagnosis of adenoid cystic carcinoma of the cribriform type of minor salivary gland, superior hemimaxillectomy and adjuvant treatment with radiotherapy and maxillofacial prosthetic rehabilitation were performed.

Highlights

  • Adenoid cystic carcinoma (ACC) is a salivary gland tumor that may originate in either major or minor salivary glands

  • Treatment for ACC consists of four distinct modalities: surgical therapy, radiotherapy, chemotherapy, and combined therapies

  • This paper presents the case of a patient with adenoid cystic carcinoma since her diagnosis to her rehabilitation

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Summary

Introduction

Adenoid cystic carcinoma (ACC) is a salivary gland tumor that may originate in either major or minor salivary glands. The ACC is a neoplasm that expresses two neoplastic cell components: ductal epithelial and myoepithelial cells; mimicking the intermediate duct of the salivary glands, its parenchyma may show tubular, cribriform, or solid morphologic pattern [5] It is a slow growing and painless mass; pain symptoms may be present due to the predisposition to invade tissues and nerves [4, 5]. Treatment for ACC consists of four distinct modalities: surgical therapy, radiotherapy, chemotherapy, and combined therapies (surgery and radiotherapy; radio and chemotherapy) The latter has been the modality of choice in most cases, because only surgical removal or radiation therapy does not discard the possibility of recurrence in the margins nor metastases to occur mainly in the cervical lymph nodes, lungs, bones, and brain [5,6,7]. This paper presents the case of a patient with adenoid cystic carcinoma since her (late) diagnosis to her rehabilitation

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