Abstract
胃肠道是人体最大的淋巴器官,其黏膜免疫系统在机体担负第一线的局部防御任务.黏膜免疫和系统免疫不同,主要发挥免疫抑制作用.调节性T细胞(Tr)是近年来免疫学领域的热点之一,其主要在机体免疫系统中发挥负向调节作用,既能抑制不恰当的免疫反应,又能限定免疫应答的范围、程度及作用时间.大量研究表明,Tr与胃肠道黏膜的过敏、感染及自身免疫性疾病有关.该文对近年来文献报道的Tr在胃肠道黏膜免疫中的作用及潜在应用价值作一综述.
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