Abstract
Substances regulating sexual reproduction in yeasts have been investigated chemically. From cells of mating type α each of two species of Saccharomyces, peptides were isolated which induce sexual agglutinability in cells of the opposite mating type a. The peptides were found to differ in their amino-acid sequences but showed cross interaction between the two species of yeasts. In Rhodosporidium, a novel lipopeptide, rhodotorucine A, was found, produced by cells of mating type A to induce mating tube formation in the opposite mating type a cells. Rhodotorucine A was also shown to be metabolized specifically by a cells into two inactive peptide fragments.
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