Abstract
The pathophysiological mechanism of neuropathic pain is complicated, and there is no perfect treatment at present. The study on mechanism of neuropathic pain can help to find appropriate therapeutic methods. Glial cells are non-neuronal cells that play crucial roles on maintaining neuronal homeostasis in central nervous system. There are increasing evidences that glial cells play significant roles on the development and maintenance of neuropathic pain, and the pathological state of pain is related to the activation status of different glial cells. In this paper, we review the roles of glial cells in neuropathic pain that could provide new ideas and directions for the treatment of neuropathic pain. Key words: Neuropathic pain; Microglia; Astrocyte; Oligodendrocyte; Schwann cell; Satellite glial cell
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