Abstract
Human T-cell clones to bee venom phospholipase A2 (PLA), isolated from allergic, hyposensitized and hyperimmune individuals to bee sting, secrete both IL-4 and IFN-γ after antigen stimulation. However, the production of IL-4 was higher than the production of IFN-γ. The threshold of the antigen dose required for IL-4 secretion was lower than for IFN-γ. Furthermore, clones derived from allergic and hyposensitized individuals generally expressed increasing ratios of IL-4/IFN-γ production with increasing concentrations of PLA. In contrast, most clones isolated from hyperimmune subjects expressed an opposite dose relationship for IL-4/IFN-γ production.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
