Abstract

Regression of functional brain networks in early Alzheimer’s disease

Highlights

  • We described selectively disturbed default and executive attention networks among several resting-state networks (RSNs) in patients with mild cognitive impairment (MCI) at high risk for Alzheimer‘s Disease (AD)

  • The maturing brain has recently been analyzed with resting-state functional connectivity MRI

  • Intrinsic brain activity were found to be similar to resting-state networks (RSNs) previously described in adults

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Summary

Introduction

We described selectively disturbed default and executive attention networks among several RSNs in patients with mild cognitive impairment (MCI) at high risk for Alzheimer‘s Disease (AD). The maturing brain has recently been analyzed with resting-state functional connectivity MRI (rs-fcMRI). Intrinsic brain activity were found to be similar to resting-state networks (RSNs) previously described in adults. Distant regions of the default network have only been sparsely connected.

Results
Conclusion
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