Abstract
AbstractThe regioselectivity of radical addition and cyclization reaction of tertiary enamides between 5‐membered benzoyl group and 5/6/7‐membered benzyl group ring closure was investigated, and trifluoroethyl ‐containing N‐Acyl isoindolines, N‐acyl tetrahydro‐isoquinolines, and N‐benzoyl tetrahydro‐1H‐benzo[c]azepine were obtained in moderate to good yields with high atom economy. Possible reaction pathway for the formation of the products was also discussed in this paper.magnified image
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