Abstract
The segregation of human glutathione peroxidase-1 (GPX1, EC 1.11.1.9) was followed in a series of human-mouse somatic cell hybrids carrying various fragments of human chromosome 3. These fragments originated from translocations in the parental human fibroblasts or from spontaneous deletions which occurred during the cultivation of hybrid clones. The smallest region of overlap found for the position of GPX 1 was 3p13→3q12.
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