Regional differences in endometrial cancer treatment and outcomes: A provincial study

Abstract

5095 Background: The optimal treatment strategy for endometrial cancer is controversial, and there is lack of treatment standardization across the province of Ontario. The objective of this study is to compare endometrial cancer treatment and outcomes among five centres in Ontario, Canada. Methods: This was a retrospective cohort study of women diagnosed with endometrial cancer in Ontario between 1996 and 1998. Approximately 30–50 patient charts were randomly selected by medical records at each of five health care centres in Ontario. Study outcomes included overall and disease-free survival, rates of adjuvant radiotherapy, complications of treatment, and predictive factors for survival. Results: There were 195 women in this cohort. The two different treatment strategies were total abdominal hysterectomy and bilateral salpingo-oophorectomy (TAH BSO) and surgical staging (TAH BSO and pelvic lymph node dissection). There was a wide range of staging practices across the province; none of the patients in Kings...