Retrospective analysis of cases with Endometrial Cancer

Abstract

We planned this study with the aim of determining histological types, clinical, surgical stage and grade of endometrial cancer cases which were followed-up and operated on in our clinic and giving an opinion on epidemiological features. Our study was a retrospective study consisted of 298 patients who had medical operations with the diagnosis of endometrial cancer. Endometrial cancer was diagnosed via dilatation and curettage. Routine preoperative examinations were wanted from the cases. Clinical stage was determined. After the diagnosis, total abdominal hysterectomy and bilateral salpingo-ooforectomy (TAH+BSO) were applied; while only pelvic lymph node dissection was applied on the patients who had good prognostic data, total pelvic and paraaortic lymph node dissection were applied to the group with bad prognostic data. All materials were examined in the pathology laboratory of our hospital. In endometrial cancer staging, FIGO surgical staging system -2009 was used. FIGO was used in grade classification and World Health Organization Classification of Tumors system was used for the histological classification. Our study was composed of 298 patients who had endometrial cancer. Of the patients who were included in the study, average age was 56.54±9.69, BMI average was 31.47±6.20, gravida average was 4.16±2.59, and parity average was 3.41±2.15. Distributions of the patients by surgical stages were as follows; there were 32 patients whose tumor stage was in 1A (%10.7), 127 patients in 1B (42.6%), 47 patients in 1C (15.8%), 18 patients in 2A (6.0%), 7 patients in 2B (2.3%), 30 patients in 3A (10.1%), 2 patients in 3B (0.7%), 30 patients in 3C (10.1%), 2 patients in 4A (0.7%) and 3 patients in 4B (1.0%). Of the patients with endometrial cancer in our study, tumors of 102 patients were (34.2%) in grade I, 139 were (46.6%) in grade II and 57 were (19.1%) in grade III. Because endometrial cancer shows earlier symptoms than the other gynecological cancers, it can be diagnosed in early stages. There is a surgical standard treatment, but it changes according to the stages and general state of the patients.