Abstract
What do degenerative disc disease, mobile spondylolisthesis, and posttraumatic syringomyelia have in common? They are all conditions potentially treatable with stem cell injections. Mesenchymal stem cells (MSCs) are playing an increasingly significant role in research for spine and spinal cord injury (SCI) applications. In vitro and in vivo experiments involving intervertebral discs (IVDs), bone development in spinal fusion, and SCI are performed with increasing frequency. The purported key to success in the implantation of MSCs in human tissue is creating an in vivo environment in which the MSCs will be able to differentiate into their anticipated terminal cell type. Investigators are, in fact, discovering that the MSCs are involved in cell and tissue repair in a number of ways.
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