Abstract
Objective: Human immunodeficiency virus (HIV), a lentivirus (member of the retrovirus family) causing acquired immunodeficiency syndrome (AIDS), weakens the immune system of the body and hence associates different opportunistic infections. Present study undertook a survey on opportunistic infections. Materials and Methods: Data were collected from both HIV carriers (CD4 count more than 250/mL of blood) and AIDS patients (CD4 count less than 250/mL of blood). Results: Analyses of the data revealed that diarrhoea, pulmonary tuberculosis, gland tuberculosis, skin lesions and fever were the common opportunistic infections. Conclusion: It can be summarized that HIV infected patients having a reduced CD4 count (<250/mL) encounter different opportunistic infections and some of these infections could be continual for long as well. DOI: http://dx.doi.org/10.3329/bjms.v13i3.19151 Bangladesh Journal of Medical Science Vol.13(3) 2014 p.285-291
Highlights
Human immunodeficiency virus (HIV) causes progressive impairment of the body’s cellular immune system leading to the increased susceptibility to tumors, and the fatal conditions known as AIDS1
acquired immunodeficiency syndrome (AIDS) is a disease in which the body's immune system breaks down and is unable to fight off infections, known as ‘opportunistic infections,’ and other illnesses that take advantage of a weakened immune system
HIV infection leads to low diagnosis and treatment of opportunistic infections levels of CD4 T cells through three main mecha- is an integral part of this treatment
Summary
HIV causes progressive impairment of the body’s cellular immune system leading to the increased susceptibility to tumors, and the fatal conditions known as AIDS1. The unique feature in the pathogenesis of HIV/AIDS is that the primary target lost, and the body becomes progressively more susceptible to opportunistic infections, for example, pneumocystis pneumonia, toxoplasmosis, cryptococcosis, etc[3]. In this way, AIDS related mortality and morbidity, which is significantly higher in number as compared to other diseases, is due to opportunistic infections rather than HIV itself 4. The success of any HIV/AIDS care and management support relies on effective diagnosis and treatment of opportunistic infections. Diagnosis of nisms: first, direct viral killing of infected cells; sec- CD4 cell count is best validated predictors of likeliond, increased rates of apoptosis in infected cells; hood of developing opportunistic infections
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