Abstract
The occurrence of artifacts is a major challenge in photoacoustic imaging. The artifacts negatively affect the quality and reliability of the images. An approach using multi-wavelength excitation has previously been reported for in-plane artifact identification. Yet, out-of-plane artifacts cannot be tackled with this method. Here we propose a new method using ultrasound transducer array displacement. By displacing the ultrasound transducer array axially, we can de-correlate out-of-plane artifacts with in-plane image features and thus remove them. Combining this new method with the previous one allows us to remove potentially completely both in-plane and out-of-plane artifacts in photoacoustic imaging. We experimentally demonstrate this with experiments in phantoms as well as in vivo.
Highlights
Recent research has shown numerous potential clinical applications of photoacoustic imaging (PAI) [1,2,3]
We propose a method for suppression of the of-plane artifacts (OPAs) by axially displacing the US transducer array
Combining two methods We have previously reported a method for identifying in-plane artifacts (IPAs) using multiwavelength excitation [14]
Summary
Recent research has shown numerous potential clinical applications of photoacoustic imaging (PAI) [1,2,3]. This imaging technique is based on the photoacoustic (PA) effect. Samples are illuminated using short pulsed laser light. The local absorption of light generates ultrasound (US) waves which are detected by a US transducer. PA images are reconstructed from the detected signals providing localized information about optical absorption properties of the samples. The obtained information of endogenous chromophores such as hemoglobin helps diagnosing early stages of various diseases [2,4,5,6]
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