Abstract

PurposeTo evaluate the reduction of artifacts caused by total hip replacements (THR) in dual-layer DECT (DLCT) provided by the combination of virtual monoenergetic images (VMI) and orthopedic metal artifact reduction (MAR). Materials and MethodsA total of 24 consecutive patients carrying THR, who received DLCT, were included. Four different images were reconstructed from the same CT dataset: a) conventional images (CI), b) conventional images with orthopedic metal artifact reduction (CIMAR) c) VMI and d) VMI combined with orthopedic metal artifact reduction (VMIMAR). VMI and VMIMAR were reconstructed at 140 keV, 160 keV, 180 keV and 200 keV. Attenuation (HU) and noise (SD) were measured in order to evaluate reduction of hypodense and hyperdense artifacts, evaluate reduction of image noise as well as to calculate contrast-to-noise ratios (CNR). Image quality was additionally rated with regard to: a) extent of artifact reduction and assessment of b) pelvic organs, c) bone and d) muscle adjacent to the metal implants. Statistical analysis was performed using Wilcoxon test. ResultsVMIMAR at high keV, 140, 160, 180 and 200 keV, led to the greatest reduction of hypodense artifacts in comparison to plain VMI or CIMAR (p < 0.01), while in comparison to CI hyperdense artifacts were significantly reduced in all reconstructions (p < 0.05). Accordingly, subjective analysis found VMIMAR to be superior in reducing hypodense artifacts in comparison to VMI and CIMAR (p < 0.05), while hyperdense artifacts were equally reduced in all reconstructions compared to CI (p < 0.0001). Additionally, assessment of the pelvic organs and adjacent bone was significantly improved in VMIMAR in comparison to VMI and CIMAR (p < 0.05). In contrast, muscles adjacent to the metal implants were significantly better assessable in all reconstructions compared to CI (p < 0.01). ConclusionThe combination of VMI and MAR yields strongest reduction of hypo- and hyperdense artifacts caused by total hip replacements in staging DLCT in comparison to each technique by itself.

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