Abstract
A facile and highly efficient heterogeneous gold(I)-catalyzed hydrohydrazidation of terminal alkynes with diverse hydrazides has been developed in chlorobenzene at 60 °C by using an MCM-41-immobilized diphenylphosphine gold(I) complex [Ph2P-MCM-41-AuNTf2] as the catalyst, providing a novel and practical method for the synthesis of a wide variety of substituted keto-N-acylhydrazones in good to excellent yields. This heterogenized gold(I) catalyst was also easy to recover via filtration of the reaction mixture and was recyclable up to eight times without any apparent loss of catalytic efficiency.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call