Abstract
A case of locally recurrent leiomyosarcoma of the left seminal vesicle, previously surgically resected, is described in a 65-year-old man. The patient underwent curative radiation therapy (61 Gy/33 fractions). Initially, he experienced a complete response after irradiation, but 15 months after treatment, progressive disease was recorded both in lung and bone, without evidence of local recurrence. The lack of efficient systemic therapies leads to a poor prognosis in this disease; clinical outcome in this patient seems to suggest the utility of radiotherapy in the very rare scenario of locally recurrent seminal vesicle leiomyosarcoma.
 Bangladesh Journal of Medical Science Vol.18(1) 2019 p.156-158
Highlights
Soft tissue genitourinary tract sarcomas are rare and primary leiomyosarcomas of the seminal vesicle are exceedingly rare.[1]
We describe the first case of recurrent leiomyosarcoma of the seminal vesicle submitted to curative irradiation
Irradiation dose to whole pelvis was 45Gy in 25 fractions followed by a boost dose of 16Gy in 8 fractions on the recurrent disease, with a total dose of 61 Gy
Summary
Soft tissue genitourinary tract sarcomas are rare and primary leiomyosarcomas of the seminal vesicle are exceedingly rare.[1]. Introduction: Soft tissue genitourinary tract sarcomas are rare and primary leiomyosarcomas of the seminal vesicle are exceedingly rare.[1] In the setting of recurrent disease after a previous radical surgery, there are not guidelines about the best therapeutic approach due to the extreme rarity of this clinical scenario. We describe the first case of recurrent leiomyosarcoma of the seminal vesicle submitted to curative irradiation.
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