Abstract
A case of locally recurrent leiomyosarcoma of the left seminal vesicle, previously surgically resected, is described in a 65-year-old man. The patient underwent curative radiation therapy (61 Gy/33 fractions). Initially, he experienced a complete response after irradiation, but 15 months after treatment, progressive disease was recorded both in lung and bone, without evidence of local recurrence. The lack of efficient systemic therapies leads to a poor prognosis in this disease; clinical outcome in this patient seems to suggest the utility of radiotherapy in the very rare scenario of locally recurrent seminal vesicle leiomyosarcoma.
 Bangladesh Journal of Medical Science Vol.18(2) 2019 p.427-429
Highlights
Soft tissue genitourinary tract sarcomas are rare and primary leiomyosarcomas of the seminal vesicle are exceedingly rare.[1]
We describe the first case of recurrent leiomyosarcoma of the seminal vesicle submitted to curative irradiation
Primary malignant sarcomas arising from the urinary tract and male genital tract has been defined as urological sarcomas; the most common sites of origin are paratesticular space, prostate, bladder and kidney.[2]
Summary
Soft tissue genitourinary tract sarcomas are rare and primary leiomyosarcomas of the seminal vesicle are exceedingly rare.[1]. To the best of our knowledge no report exists on the treatment of recurrent disease. Case Report: A 65-year-old Caucasian man consulted our department in March 2013. His past history was relevant because, in July 2011, he underwent surgery for a well-differentiated leiomyosarcoma with no lymph node metastases. In January 2013, T2-weighted-MR images showed a nodule of 2.1 x 2.7 x 3.5 cm in left pararectal space, compatible with recurrent disease; 18F-FDGPET/CT demonstrated high radiopharmaceutical accumulation in that nodule (SUVmax 11.4: Figure 1). Silvana Parisi, Section of Radiological Sciences, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy 4. Stefano Pergolizzi, Section of Radiological Sciences, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy
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