Abstract
Objective: This article describes a case of a Peripheral Giant Cell Granuloma (PGCG) in a girl. Introduction: PGCG is a relatively infrequent benign reactive lesion of the gingiva or alveolar ridge that develops in response to local irritation. Clinical appearance consists of a firm or soft smooth surface nodule in dissimilar colors of varying size with sessile or pedunculated implantation base. Radiographic features are generally nonspecific, thereby definitive diagnosis depends on microscopic examination to confirm the entity of PGCG. Case Report: A 6-year-old female patient was referred to the outpatient clinic of an Oral & Maxillofacial Surgery Department with the chief complaint of an intraoral swelling. The intraoral examination showed a painless sessile mass with exophytic growth similar to a tumorous lesion located on the mandibular alveolar ridge extending from distal aspect of right mandibular primary canine to mesial aspect of first permanent molar of the same side. Conclusion: Peripheral giant cell granuloma is a relatively uncommon lesion in children and potential for collaboration with the treatment in young patients should be considered for a successful therapeutic approach.
Highlights
Peripheral Giant Cell Granuloma (PGCG) is a relatively infrequent benign reactive lesion of the gingiva or alveolar ridge that develops in response to local irritation
A distinctive feature of PGCG is the abundance multinucleated giant cells [8] which enable it to be differentiated from similar other reactive oral lesions like pyogenic granuloma and peripheral ossifying fibroma, but is the same characteristic of central giant cell granuloma [7]
Excised lesion measuring approximately 2.5x 2.0 x 1.0 cm was stored in 10% formalin and sent for histopathological examination to confirm the diagnosis of PGCG
Summary
PGCG is a relatively infrequent benign reactive lesion of the gingiva or alveolar ridge that develops in response to local irritation. Clinical appearance consists of a firm or soft smooth surface nodule in dissimilar colors of varying size with sessile or pedunculated implantation base. Peripheral giant cell granuloma clinically manifests as a painless smooth surface lesion, the size of which ranges from a few millimeters to several centimeters, brown, reddish or purple colored with sessile or pedunculate implantation base and consistency that varies from soft to firm [1, 8, 9]. A distinctive feature of PGCG is the abundance multinucleated giant cells [8] which enable it to be differentiated from similar other reactive oral lesions like pyogenic granuloma and peripheral ossifying fibroma, but is the same characteristic of central giant cell granuloma [7]. Only radiological evaluation can establish the distinction between peripheral form and central giant cell granuloma, which is an intrabony benign neoplasm of the jawbone [10]
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