Rectal mucosa prolapse caused by an intravenous infusion of amoxicillin and clavulanate potassium

Abstract

A 63-year-old female patient with bronchopneumonia received an IV infusion of amoxicillin clavulanic acid potassium 1.2 g twice daily. The patient developed nausea and rectal tenesmus about 20 minutes after the start of amoxicillin clavulanic acid potassium treatment each time on the first day. No treatments were given and the symptoms relieved gradually 3 hours after finishing the IV infusion. The patient developed the above-mentioned symptoms again about 20 minutes after the start of amoxicillin clavulanic acid potassium treatment on the second day, and rectal mucosal prolapse appeared at the same time. The amoxicillin clavulanic acid potassium was stopped immediately and an IV infusion of ceftriaxone sodium 2 g once daily was given on the third day. After 3 days of ceftriaxone sodium treatment, the patient′s cough and expectoration were improved and disappeared on the 8th day, and the rectal mucosal prolapse did not recur. Key words: Amoxicillin-potassium clavulanate combination; Rectal diseases