Abstract
Recent trends and challenges in the electrochemical methods for the detection of DNAhybridization are reviewed. Electrochemistry has superior properties over the other existingmeasurement systems, because electrochemical biosensors can provide rapid, simple andlow-cost on-field detection. Electrochemical measurement protocols are also suitable formass fabrication of miniaturized devices. Electrochemical detection of hybridization ismainly based on the differences in the electrochemical behaviour of the labelstowards the hybridization reaction on the electrode surface or in the solution. Basiccriteria for electrochemical DNA biosensor technology, and already commercializedproducts, are also introduced. Future prospects towards PCR-free DNA chips arediscussed.
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