Applications of electrochemical biosensors for cancer biomarkers detection

Abstract

In recent years, cancer has become one of the main causes of human death. If the disease develops to the middle and advanced stage, it is diffuclt to treat because the spread and mutation of cancer cells. But if the disease is detected and diagnosed at the early stage, the cure will become much easier. Therefore, research and development of early detection methods for cancer is of great importance. In view of some current cancer detection methods, electrochemical biosensors will be a good choice. Electrochemical biosensing technology has the characteristics of simple operation, low background signal, high sensitivity and easy miniaturization. It is a kind of diagnostic method which can replace the existing technology and has a good application prospect. This paper introduces several feasible electrochemical biosensors for detection of cancer biomarkers, including electrochemical biosensor constructed by peptide hydrogel, nanostructured superhydrophilic and superhydrophobic electrochemical biosensors, amperometric and impedance electrochemical biosensors, and electrochemical enzyme biosensor combined with various biological enzymes.