Abstract
Nanorobots have become candidates for future in vivo disease treatment due to their small size, maneuverability, and accuracy. This article reviews the current status of nanorobots in vivo imaging of ultrasound, fluorescence, magnetic resonance, radionuclide, and multimodal imaging modes. The basic principles of each imaging technology are discussed in detail. The advantages and limitations of various imaging technologies in vivo imaging of nanorobots are analyzed in terms of penetration depth, biocompatibility, and imaging rate. In addition, the differences in imaging clarity and imaging contrast between the individual mode and the cluster mode in the ultrasound mode are especially compared. The necessity of adding a contrast agent or developer to absorb, transmit, or reflect physical signals detected by an external system is also discussed. Finally, the existing challenges and solutions are summarized and prospects for in vivo applications are anticipated.
Published Version
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