Year-end Sale % OFF 
Abstract
PEDRI (Proton-electron double-resonance imaging) is a technique for imaging free radicals in animals or biological samples which is based on the Overhauser effect. It offers high sensitivity and high spatial resolution which is independent of the linewidth of the paramagnetic sample under study. In addition, it can image free radicals in large animals, potentially even in humans. PEDRI is a double-resonance method for imaging free radicals which relies on the Overhauser effect. A proton MR image of the sample is recorded while an electron paramagnetic resonance (EPR) resonance of the free radical is irradiated. In this way high resolution images of the free radical distribution can be obtained. Field-cycled PEDRI improves the sensitivity and reduces the RF power deposition by switching the magnetic field during the pulse sequence. Applications of PEDRI and Field-cycled PEDRI include the pharmacokinetics of exogenous free radical contrast agents as well as the determination of local oxygen concentration and pH via their effect on exogenous agents. The detection and imaging of endogenous free radicals is more challenging, but may become feasible by virtue of improvements in techniques.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
