Abstract
Despite the fact that in the majority of cases rhinosinusitis is known to be viral, bacterial infections still play their role. Bacterial etiology for sinonasal pathology usually means more severe condition, chronic forms and frequent recurrence. Treatment of acute bacterial rhinosinusitis with systemic antibiotics is a challenging question. Unappropriate use of systemic antibiotics not only leads to individual treatment failure, but also causes global epidemiologic issues such as antibiotic resistance. The article reviews the role of respiratory fluoroqionolones in medical treatment of patients with moderate to severe bacterial rhinosinusitis.
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