A clinician’s guide to the appropriate and accurate use of antibiotics: the Council for Appropriate and Rational Antibiotic Therapy (CARAT) criteria

Thomas G Slama,Alpesh Amin,Stephen A Brunton,Thomas M File,Gary Milkovich,Keith A Rodvold,Daniel F Sahm,Joseph Varon,David Weiland

doi:10.1016/j.amjmed.2005.05.007

A clinician’s guide to the appropriate and accurate use of antibiotics: the Council for Appropriate and Rational Antibiotic Therapy (CARAT) criteria

Thomas G Slama, Alpesh Amin + Show 7 more

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https://doi.org/10.1016/j.amjmed.2005.05.007

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Journal: The American Journal of Medicine	Publication Date: Jul 1, 2005
Citations: 80

Affiliation: University of Illinois at Chicago, University of California, Irvine Medical Center, University of South Florida, Carolinas Medical Center, Indiana University Indianapolis, Northeast Ohio Medical University, Ohio University, The University of Texas Health Science Center at Houston

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Abstract

In response to the overuse and misuse of antibiotics, leading to increasing bacterial resistance and decreasing development of new antibiotics, the Council for Appropriate and Rational Antibiotic Therapy (CARAT) has developed criteria to guide appropriate and accurate antibiotic selection. The criteria, which are aimed at optimizing antibiotic therapy, include evidence-based results, therapeutic benefits, safety, optimal drug for the optimal duration, and cost-effectiveness.

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