Recent Developments in Mass Spectrometry in Biochemistry and Medicine

Abstract

The Place of Mass Spectrometry in Drug Metabolism Studies.- In vitro and in Vivo Studies on the Metabolism of Dibenzo [c,f]--[1,2] Diazepine.- Gas Chromatographic-Mass Spectrometric Identification of Urinary Metabolites of Propildazine in Rat.- Mass Spectrometric Characterization of Sydnocarb (R) and its Major Metabolites in Rat.- Metabolism of an Aryloxy Beta Blocking Drug.- Isolation and Identification of the Chloroform Soluble Urinary Metabolites of Suloctidil in Man.- Are Stable Sulfenic Acids Possible Metabolites of Suloctidil?.- The Electron Impact Fragmentation of Products Related to N-(Allyl)-3,3-Diphenylpropylamine, a Metabolite from Thiopropamine (R).- Urinary Metabolites from (2-Ethyl-2,3-Dihydro-5-Benzofuranyl) Acetic Acid.- The Major Metabolites of Niclosamide: Identification by Mass Spectrometry.- The Metabolism of Deuterium-Labelled Analogues of ?1-, ? 6-, and ? 7-Tetrahydrocannabinol and the Use of Deuterium Labelling.- Kinetics of Degenerate Nucleophilic Exchange of C(3)-Hydroxy Group in l-Methyl-3-Hydroxy- -5-Phenyl-7-Cloro-2H-l,4-Benzodiazepin-2-One.- On the Analysis of Fermentation Broth During Biosynthesis of Cephalosporin Antibiotics.- GC-MS Analysis by Electron Impact Ionization and Chemical Ionization of Carcinogenic 2-Acetylaminofluorene and its Metabolites.- The Proximo-Distal Carcinogen of the K Region of Benzo (a)Pyrene.- Quantitative Determination of Vincamine in Human Plasma by Gas Chromatography - Mass Spectrometry.- Mass Fragmentographic Quantification of Phosphonoacetic Acid in the Blood of Monkeys Infected with Herpesvirus Saimiri.- The Determination of Blood Cyanide and Plasma Thiocyanate by Gas Chromatography-Mass Spectrometry.- Present State and Future Trends of Negative Ion Mass Spectrometry in Toxicology, Forensic and Environmental Chemistry.- Mass Fragmentographic Determination of Polyamines in the Urine of Premature Babies.- An Assay for Schizophrenia: Mass Spectrometric Determination of Two Cadaverine Metabolites.- Analysis of the Urinary Steroids from a Pathological Pregnancy by Liquid-Gel Chromatography and Gas-Chromatography-Mass Spectrometry.- Identification of Atypical Bile Acids by Gas Chromatography-Mass Spectrometry-Computer Techniques.- The Effects of Triisopropylacetic Acid on the Metabolic Profile of Urinary Organic Acids.- Application of Chemical Ionization MS to the Study of Regional Brain Catecholamine Metabolism in (S)-?-Methyldopa Treated Rats.- Concurrent Extraction and GC-MS Assay of Endogenous TP, T, IAA, 5HT and 5HIAA in Single Rat Brain Samples.- A New Method for Simplified Prostaglandin Profiling by Selected Ion Monitoring.- Analysis of Urinary Steroids by Liquid-Gel Chromatography and Gas Chromatography - Mass Spectrometry. Clinical Applications.- A Micromethod for the Clinical Chemistry Routine Analysis of Amino Acids in Blood and Urine by Capillary Gas Liquid Chromatography of Isobutyl Esters N(O)-Heptafluorobutyrate Derivatives.- Metabolic Profile of Ventricular Cerebrospinal Fluids.- Energy and Metastable Characteristics in Peptides, Electron Impact Appearance Potentials of Sequence Ions in Tripeptides.- The Continuous Recording of Expired C16O18O by Respiratory Mass Spectrometry After Injection of H218O into the Vascular System.- A Continuous Mass Spectrometric Analysis of Expired Physiological Gases: the Pulmonary Gas Exchange.- Adaptation of Respiratory Mass Spectrometer to Continuous Recording of Abundance Ratios of Stable Oxygen Isotopes.- The Development of a Flexible Mass Spectrometer Catheter.- Contributor Index.