Abstract
Tissue engineering is a relatively new area of research that combines medical, biological, and engineering fundamentals to create tissue-engineered constructs that regenerate, preserve, or slightly increase the functions of tissues. To create mature tissue, the extracellular matrix should be imitated by engineered structures, allow for oxygen and nutrient transmission, and release toxins during tissue repair. Numerous recent studies have been devoted to developing three-dimensional nanostructures for tissue engineering. One of the most effective of these methods is electrospinning. Numerous nanofibrous scaffolds have been constructed over the last few decades for tissue repair and restoration. The current review gives an overview of attempts to construct nanofibrous meshes as tissue-engineered scaffolds for various tissues such as bone, cartilage, cardiovascular, and skin tissues. Also, the current article addresses the recent improvements and difficulties in tissue regeneration using electrospinning.
Highlights
Tissue engineering has caught the attention of many domains that have collaborated to find new solutions to produce cells and tissues naturally in the laboratory [4]
The collaboration of many medical and biomedical fields is working on enhancing the tissue engineering process and making it more efficient to be used in treatment [8]
The scaffolds improved hMSC osteogenic differentiation and HUVEC angiogenic activity. These findings show that such polymer/ceramic nanofibrous scaffolds have multi-biofunctional properties and are viable options for bone tissue regeneration scaffolds [69]
Summary
The biomedical industry has contributed on a large scale with technologies in treatment that has led to healthier lives in patients. It is referred to as regenerative medicine This type of treatment in the medical field is the way to the future of medicine and the biomedical field for reasons such as the disuse of medication and drugs and the growth of cells in the lab that are mainly from the body to the body of the subject [4–6]. The collaboration of many medical and biomedical fields is working on enhancing the tissue engineering process and making it more efficient to be used in treatment [8]. The collaboration mentioned earlier focuses on enhancing the scaffold that the tissue would grow in; the main goal in this research is to find the most efficient method for the biocompatible scaffold to allow the tissue to grow completely without burdens and complications [4]. The current article discusses the benefits and drawbacks of using electrospinning for tissue regeneration
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