Abstract
Glucose plays an important role in cardiac metabolism.It is the major energy source during myocardial ischemia.Trans-membrane glucose transport is the first rate-limited step for myocardial glucose metabolism,which is facilitated by glucose transports (GLUTs) and GLUT4 represents an important mechanism that governs the entry of glucose into the heart.The quality and quantity of GLUT4 play a decisive role in transmembrane glucose transport.To better retrieve myocardial metabolism and improve myocardial function under myocardial ischemia conditions,it is urgent to elucidate the regulatory mechanism of GLUT4 expression,the regulatory mechanism of GLUT4 translocation,the regulatory mechanism of GLUT4 intrinsic activity and glucose transport in cardiomyocytes.This review summarized the current state of knowledge regarding the regulation of GLUT4 functioning and glucose transport in cardiomyocytes. Key words: Glucose transport proteins, facilitative; Glucose transporter type 4; Myocytes, cardiac; Myocardial ischemia
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Radiation Medicine and Nuclear Medicine
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
