Abstract
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Highlights
The cutaneous wound healing process closes skin gaps by inducing the formation of granulation tissue and epithelialization, which re-establishes an effective epidermal barrier
Horng et al [1] showed in the Special Issue that estrogen deficiency, such as that in postmenopausal women, has detrimental effects on wound-healing processes, inflammation and re-granulation, and that exogenous estrogen treatment may reverse these effects [1]
Akita et al showed that proper epithelialization plays an important role in the healing of burn wounds: when patients with extensive burns received cultured epithelial autografts (CEA) along with either highly expanded or less expanded mesh, the former combination was associated with accelerated wound healing
Summary
The cutaneous wound healing process closes skin gaps by inducing the formation of granulation tissue and epithelialization, which re-establishes an effective epidermal barrier. Horng et al [1] showed in the Special Issue that estrogen deficiency, such as that in postmenopausal women, has detrimental effects on wound-healing processes, inflammation and re-granulation, and that exogenous estrogen treatment may reverse these effects [1].
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