Recent Advances in Organocatalytic Synthesis and Catalytic Activity of Substituted Pyrrolidines

Abstract

Abstract: The emergence of enantioselective organocatalysis as a potent synthetic chemistry strategy that supports metal-catalyzed transformations has resulted in the creation of novel procedures for the synthesis of various chiral molecules. Organocatalysis is a desirable method for creating complex molecular structures due to its many benefits, including its ease of use, wide availability of catalysts and low toxicity. Chemists are actively exploring synthetic methodologies and looking into the applications of pyrrolidine-based organocatalysts. The application of organocatalysts spans a wide range of reaction types, highlighting their ability to participate in a variety of catalytic processes. The current study offers a succinct summary of the principal strategic methods for producing pyrrolidine-based organocatalysts and demonstrating their usefulness in organic transformations.