Recent advances in injectable nanocomposite hydrogels

Abstract

Injectable nanocomposite hydrogels, known for their striking similarity to the native extracellular matrix and their minimally invasive application method, stand out as promising biomaterials within the realms of tissue engineering and drug delivery. The capability of hydrogels can be improved with a diverse spectrum of nanoparticles (NPs) such as graphene oxide, carbon nanotubes, ceramics, and metallic-based NPs, along with synthetic and natural polymers. This integration forms nanocomposites that enhance remarkable mechanical and biological attributes. This review sheds light on the latest advancements in the deployment of injectable nanocomposite hydrogels for biomedical and pharmaceutical purposes. Specifically, it explores the synthesis techniques and characteristics of these nanocomposite hydrogels and articulates their role in facilitating wound healing, combating bacterial infections, and achieving clinical milestones. The review concludes by offering a vision for the future, highlighting the potential for more advanced developments in injectable nanocomposite hydrogels for enhanced biomedical applications.=