Abstract

The electrochemical detection of glucose concentration without using enzymes have recently created overwhelming demand in the field of glucose sensors. The demand to fabricate non-enzymatic glucose sensors (NEGS) that have high sensing capabilities and biocompatibility has increased tremendously. Extensive research has been geared towards the fabrication of non-enzymatic glucose sensors using novel materials. Graphene, due to its astounding properties, has provided a detailed insight into NEGS application. This review article highlights the advantages and disadvantages of different electrode material such as platinum, transition elements, gold, precious metal, non precious metals, Carbon Nano tube (CNT) and graphene based electrodes and their contribution in glucose detection in terms of sensitivity and detection limit. The electrodes have been modified by different transition elements, nano particles and binary alloys keeping in mind the electrocatalytic action and synergistic effect which enhance the glucose sensing mechanism drastically. It is observed that polymer based graphene electrodes have many advantages over other electrode for glucose sensing because of its remarkable electrocatalytic and synergistic properties.

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