Abstract
Endophytes, found ubiquitous in all plant species in the world, contribute to their host plants by producing many substances that provide protection and ultimately survival value to the plant. Many researches have proven that endophyte is a new and potential source of novel natural products for exploitation in modern medicine, agriculture and industry. So far, a great number of novel natural products possessing antimicrobial activities have been isolated from endophytes especially fungal endophytes. It is believed that screening for antimicrobial compounds from endophytes is a promising way to overcome the increasing threat of drug-resistant strains of human and plant pathogens. Antimicrobial metabolites isolated from endophytes belong to diverse structural classes, including alkaloids, coumarins, flavonoids, glycosides, quinones, peptides, phenols, steroids, terpenoids, and volatile organic.
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