Recent advances in accelerating solid-phase extraction

Abstract

With the growing demand for rapid processing of laboratory samples, great efforts have been dedicated to improving the speed and throughput of solid phase extraction (SPE), a widely used sample pretreatment technique. This review comprehensively summarizes the latest advancements in accelerating SPE within the last five years, with a focus on three crucial aspects: novel extraction materials, field-assisted technology, and online coupling. It provides an update of the remarkable features and applications of advanced and novel sorbents, as well as novel devices used in SPE. The mainstream approach for accelerating SPE continues to be the development of novel sorbents with large surface area and high porosity. Additionally, promising results have been achieved through the design of novel devices for field-assisted SPE or highly integrated online SPE systems. This review also addresses current limitations and presents future prospects for the acceleration of SPE. By consolidating recent developments and discussing potential directions, this review endeavors to shed light on the path towards faster and more efficient SPE, imparting substantial benefits to various analytical applications.