Abstract
Real-time 4D full-range complex-conjugate-free Fourier-domain optical coherence tomography (FD-OCT) is implemented using a dual graphics processing units (dual-GPUs) architecture. One GPU is dedicated to the FD-OCT data processing while the second one is used for the volume rendering and display. GPU accelerated non-uniform fast Fourier transform (NUFFT) is also implemented to suppress the side lobes of the point spread function to improve the image quality. Using a 128,000 A-scan/second OCT spectrometer, we obtained 5 volumes/second real-time full-range 3D OCT imaging. A complete micro-manipulation of a phantom using a microsurgical tool is monitored by multiple volume renderings of the same 3D date set with different view angles. Compared to the conventional surgical microscope, this technology would provide the surgeons a more comprehensive spatial view of the microsurgical site and could serve as an effective intraoperative guidance tool.
Highlights
Microsurgeries require both physical and optical access to limited space in order to perform task on delicate tissue
Visualization during the operation is realized by surgical microscopes, which limits the surgeon’s field of view (FOV) to the en face scope [1], with limited depth perception of micro-structures and tissue planes
As a noninvasive imaging modality, optical coherence tomography (OCT) is capable of cross-sectional micrometer-resolution images and a complete 3D data set could be obtained by 2D scanning of the targeted region
Summary
Microsurgeries require both physical and optical access to limited space in order to perform task on delicate tissue. The surgeon needs to function within the limits of human sensory and motion capability to visualize targets, steadily guide microsurgical tools and execute all surgical targets. The recent developments of graphics processing unit (GPU) accelerated FD-OCT processing and visualization have enabled realtime 4D (3D + time) imaging at the speed up to 10 volume/second [8,9,10] These systems all work in the standard mode, and suffer from spatially reversed complexconjugate ghost images. Multiple volume rendering of the same 3D data set were preformed and displayed with different view angles This technology can provide the surgeons with a comprehensive intraoperative imaging of the microsurgical region which could improve the accuracy and safety of the microsurgical procedures
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