Abstract
Abstract Zinc silicate and zinc beryllium silicate were injected intratracheally into two groups of guinea pigs. Serial sacrifice of the animals was made and the pathology of lesions of the lungs was studied. Zinc silicate produced lesions comparable to but less severe than those from zinc beryllium silicate. Lesions from zinc silicate reached maximal intensity in about eight weeks; thereafter, recovery was noted and at 14 months a normal pulmonary parenchyma was restored. The beryllium salt produced more advanced lesions in two weeks with progression for three or four months. At 15 months some residual injury remained.
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