Abstract

2-Benzyl- and 2-(2-chlorobenzyl)-5-phenylisoxazolidine-3-thiones 1 and 2-benzyl-5-phenylisoxazolidin-3-one 2 react with aromatics such as toluene, biphenyl, p-xylene, and chlorobenzene in the presence of anhydrous aluminum chloride, in dichloromethane at room temperature to give 3-aryl-N-benzyl-3-phenylpropanothiohydroxamic acids and 3-aryl-N-benzyl-3-phenylpropanohydroxamic acids in good yields.

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