Re-irradiation spine SBRT in oligoprogression breast cancer: A case report

Abstract

Stereotactic body radiotherapy has experienced exponential development in recent years, as its ablative capacity has demonstrated a benefit in certain patients including oligometastatic and oligoprogressive patients. We present a case of a 59-year-old woman with a history of infiltrating metastatic ductal breast carcinoma with vertebral bone oligoprogression. After radical surgical treatment and re-irradiation SBRT, a complete response was achieved. After more than two years of follow-up the patient remains with neither local nor distant recurrence. Patients with oligometastatic or oligoprogressive breast cancer are candidates for radical treatment modalities. Stereotactic body radiotherapy has demonstrated promising local control, progression free survival and overall survival in these patients. In this context, there are currently ongoing phase III studies in order to provide stronger evidence.