Abstract
Sir — We are pleased to see non-radiologists taking an active interest in our journal, Clinical Radiology. We are also delighted to engage with fellow enthusiasts of MRA. However, we think Mr Chaudhuri has missed the specific purpose of our investigation, namely high-resolution extended-phase infra-inguinal imaging. Furthermore, this was indeed a pilot study as our concluding paragraph made clear. Following this pilot, we have undertaken a larger prospective study at our institution in which we have included gadobutrol in intra-individual comparisons, and we hope to publish this in the near future. Re: Comprehensive MRA of the lower limbs including high-resolution extended-phase infra-inguinal imaging with gadobenate dimeglumine: Initial experience with inter-individual comparison to the blood-pool contrast agent gadofosveset trisodiumClinical RadiologyVol. 68Issue 10PreviewSir — I was interested to read the above article comparing “newer” standard (gadobenate) versus blood-pool contrast agents (BPCA; gadofosveset) for lower-limb magnetic resonance angiography (MRA) in a somewhat small series of 20 patients.1 If MRA is indeed the authors' standard peripheral arterial imaging method, and more numbers could have been provided, then the samples are surely somewhat inadequate, given that even a basic tool such as Altman's nomogram (before going on to more complex calculations) would suggest sample sizes of 200 for starters, in order to obtain a meaningful analysis. Full-Text PDF Comprehensive MRA of the lower limbs including high-resolution extended-phase infra-inguinal imaging with gadobenate dimeglumine: Initial experience with inter-individual comparison to the blood-pool contrast agent gadofosveset trisodiumClinical RadiologyVol. 68Issue 2PreviewTo compare extended-phase imaging using an extracellular space contrast agent, gadobenate dimeglumine, to imaging with a blood-pool contrast agent, gadofosveset, for magnetic resonance angiography. Full-Text PDF
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