Abstract
RBE values were obtained from the delay in regrowth of first-generation transplanted mammary carcinomas after irradiation with single doses of X-rays or neutrons. A decrease of RBE with increasing dose to a minimum value of 2·6± 0·6 at about 600 rads of neutrons was found. The results agree with those obtained previously for delay in regrowth and also for local control of tumours in multi-fraction experiments using small doses per fraction. The RBE values for this carcinoma were not significantly greater than RBE's for skin reactions at low doses per fraction, as was predicted from their shrinkage pattern after large doses of X-rays and their known reoxygenation kinetics.
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