Abstract

 Infection is one of the biggest causes of death in Indonesia which can be influenced by the appropriate use of antibiotics. Irrational use of antibiotics can cause bacteria to become resistant to antibiotics so that the effectiveness of the drug decreases or even disappears. This study aims to evaluate the use of antibiotics given to inpatients at a private hospital in Indonesia both quantitatively and qualitatively in the period July to December 2021. This study is an observational study with retrospective data collection where qualitative analysis using the Gyssens Method and quantitative analysis uses the DDD method. The results of the qualitative analysis showed that from 30 cases observed, there were 9 cases (30%) irrational prescriptions, namely 1 case in category V, 4 cases in category IVA, 2 cases in category IIIB and 2 cases in category IIA. The results of the quantitative analysis showed that the antibiotics with the highest DDD/100 patient days in the period July to December 2021 were Ceftriaxone with a successive value of 39.15; 39.81; 36.22; 55.65; 41,48 and 49, 42 while antibiotics with the lowest DDD/100 patient-days values in the period July to December obtained different results. Based on research results, there are irrational antibiotic prescriptions and Ceftriaxone became the most commonly prescribed antibiotic.
 
 
 
 
 
 
 
 
 
Highlights
Infection is a health problem that is one of the causes of death and illness in hospitals and other health care facilities in Indonesia
The use of antibiotics in patients should pay attention to the time, dose and duration of administration according to the therapeutic regimen as well as patient compliance with the use of antibiotics, if this is neglected it can be at risk of causing bacteria resistant to antibiotics (Indonesian Ministry of Health, 2011)
Of the 30 cases used as sample data in this research, there were a total of 9 cases in which the administration of antibiotics could be said to be irrational
Summary
Antibiotics are the drug of choice used to treat infectious diseases. The use of antibiotics in patients should pay attention to the time, dose and duration of administration according to the therapeutic regimen as well as patient compliance with the use of antibiotics, if this is neglected it can be at risk of causing bacteria resistant to antibiotics (Indonesian Ministry of Health, 2011). Resistance occurs when bacteria are no longer sensitive to the action of antibiotics or antibiotics are unable to eradicate bacteria due to loss of drug effectiveness. Especially if multi-drug resistance is a problem that will be difficult to overcome. When the patient is already resistant to an antibiotic, another antibiotic that is more effective must be chosen so that infectious diseases can be treated properly
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