Abstract

This article presents data on the export of raw materials and the results of pharmacological studies of caper buds for use in the pharmaceutical industry. For this, the volumes of export products for the last 2 years were studied and preclinical studies of the aqueous-alcoholic extract obtained from local plant materials were carried out in comparison with reference preparations. As a result, the aqueous-alcoholic extract obtained from local plant materials has reliable hypoglycemic activity comparable to the reference preparation “Gluqueir” capsule, but inferior to the synthetic preparation “Diabeton MR” 60 mg tablets with modified release. The range of effective doses (ED30, ED50 and ED100) was also established and the most effective dose was found.

Highlights

  • A number of government decrees have been adopted in Uzbekistan on the rational use of natural resources of medicinal plants, the cultivation of rare and demanded species in the pharmaceutical industry, as well as their wider application in medical practice

  • These plants include prickly capers, which is recommended to be cultivated in the foothill and plain land areas of Bostanlyk and Akhangaran districts of Tashkent province, Zaamin, Bakhmal, Gallaaral and Farish districts of Jizzakh province, Pap and Chust districts of Namangan, Navoi, Kashkadarya and Surkhandarya provinces

  • Considering these circumstances, from the buds of prickly capers and leaves of honey stevia, harvested from local raw materials, an aqueous-alcoholic extract was obtained for further pharmacological studies

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Summary

Introduction

A number of government decrees have been adopted in Uzbekistan on the rational use of natural resources of medicinal plants, the cultivation of rare and demanded species in the pharmaceutical industry, as well as their wider application in medical practice. The Decree of the President of the Republic of Uzbekistan dated April 10, 2020 No PP-4670 "On measures for the protection, cultivation, processing of wild medicinal plants and the rational use of available resources" approved a list of provinces specializing in the cultivation of the main types of medicinal plants [1, 2] These plants include prickly capers, which is recommended to be cultivated in the foothill and plain land areas of Bostanlyk and Akhangaran districts of Tashkent province, Zaamin, Bakhmal, Gallaaral and Farish districts of Jizzakh province, Pap and Chust districts of Namangan, Navoi, Kashkadarya and Surkhandarya provinces.

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